ColestZen vs Bergamot Plus: Which Cholesterol Supplement Fits You?

Updated 2026-10-08 · HarmoHealth Editorial Team

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ColestZen and Bergamot Plus are both sold to people who want to support healthy cholesterol, and both cost roughly the same per bottle. Beyond that, they could hardly be more different. One is a wide blend of 18 herbs and nutrients; the other is a single ingredient with a stated dose. This comparison uses only the official sales pages and public research summaries.

What is the main difference between ColestZen and Bergamot Plus?

The main difference is transparency and focus. Bergamot Plus lists one active ingredient, bergamot extract, at 675 mg per tablet. ColestZen lists 18 ingredients with no amounts, and most of them are better known for blood sugar than for cholesterol.

How do ColestZen and Bergamot Plus compare side by side?

Prices were taken from each official order section in October 2026 and can change.

Which one has more research behind it?

Bergamot Plus has the advantage here, though with caveats. Bergamot extracts have been studied specifically for blood lipids: a 2022 meta-analysis of 14 trials found improvements in cholesterol and triglycerides, while calling for higher-quality studies. Neither review studied the Bergamot Plus product itself.

ColestZen's ingredients have mostly been studied one at a time for blood sugar. NCCIH's diabetes supplement summary reports some benefit for cinnamon and chromium on glucose markers and none for alpha lipoic acid over placebo. That is a different goal from lowering LDL cholesterol.

Which one is safer for people with high blood pressure?

Bergamot Plus is the simpler choice for someone with high blood pressure, because ColestZen contains licorice extract. NCCIH warns that glycyrrhizin in licorice can cause serious heart effects and that even small amounts have been linked to severe effects in people with hypertension. ColestZen does not say whether its licorice is deglycyrrhizinated or how much is included. This is a label question for your pharmacist, not something to guess at.

Which one is better if I take a statin?

Neither should be started without your prescriber. For Bergamot Plus, a 2020 systematic review noted a possible additive effect with statins, so your doctor may want to recheck your lipids. The Bergamot Plus page itself tells statin users to involve their doctor. ColestZen contains vitamin E, which may add to bleeding risk with anticoagulants, and several blood-sugar herbs that matter if you also take diabetes medicine. See our interactions guide.

Which one costs less?

At the largest bundle, ColestZen is cheaper: $49 per bottle against roughly $59 for Bergamot Plus. At the smallest bundle, both work out to about $79 per bottle plus shipping. Bergamot Plus includes free shipping from 3 bottles; ColestZen only from 6.

Which guarantee is easier to use?

ColestZen's FAQ says bottles can be returned even if empty, which sounds generous. Bergamot Plus offers a full refund minus shipping. Both are 60 days. In either case, keep your receipt, note the order date and read the return instructions at checkout.

Who should choose ColestZen?

ColestZen may suit someone who:

• has normal blood pressure and no heart rhythm or kidney issues;
• is more interested in blood sugar support than in LDL specifically;
• has shown the label to a doctor and been told the licorice content is not a concern.

Check ColestZen on the official site

Who should choose Bergamot Plus?

Bergamot Plus may suit someone who:

• wants a single, dosed ingredient they can look up easily;
• is focused on cholesterol rather than blood sugar;
• has high-normal or high blood pressure and wants to avoid licorice;
• is willing to keep their doctor informed, especially if they take a statin.

Check Bergamot Plus on the official site

What should I ask my doctor before choosing ColestZen or Bergamot Plus?

Bring the label of whichever product you are considering to your next appointment, and ask:

1. Is my cholesterol high enough that medication, not a supplement, is the right first step?
2. Does anything in this product interact with my current medicines, especially statins, blood thinners or diabetes drugs?
3. For ColestZen: is the licorice content a concern given my blood pressure and kidney function?
4. For Bergamot Plus: should my lipids be rechecked sooner if I add bergamot to a statin?
5. How long should I try it before we decide whether it is worth continuing?

A repeat lipid panel after a few months is the only reliable way to see whether anything has changed, and your doctor can tell whether a change came from the supplement, your diet or your medication.

Our verdict: ColestZen or Bergamot Plus?

For a reader whose main concern is cholesterol, Bergamot Plus is the closer match: its single ingredient is the one that has been studied for lipids, and its label is transparent. ColestZen is better described as a metabolic blend, and its licorice content makes it a harder fit for anyone with blood pressure concerns. Neither replaces a statin or dietary changes. Read the full ColestZen review, the Bergamot Plus review and our bergamot for cholesterol guide before deciding.

Sources consulted: pubmed.ncbi.nlm.nih.gov, nccih.nih.gov.